السيتيكولين له المواصفات والاستخدامات الآتية:

1. عمر النصف 71 ساعة، ويزيد من مستوى الدوبامين في الدماغ، ويجب إعطاؤه بحذر مع الأدوية المضادة للباركنسون (ليفودوبا).
2. اضطراب فرط الحركة ونقص الانتباه: يزيد السيتيكولين من الانتباه ويعزز فرط النشاط.
3. فعال للغاية في إصابات الدماغ الحادة: صدمة الدماغ واحتشاء الدماغ والنزيف. يجب إعطاؤه 2000 مجم يوميًا.
4. فعال في تأخر النمو العصبي.
5. فعال في مرض الزهايمر والاضطراب ثنائي القطب.
6. فعال في الاكتئاب حيث يتم إعطاؤه 100 مجم كل 12 ساعة مع سيتالوبرام.

Citicoline has the following characteristics and uses:

1. Half-life is 71 hours.
2. Increases dopamine level in the brain, and should be given with caution with anti-PD drugs (levodopa).
3. ADHD: citicoline increases attention and enhances hyperactivity.
4. Very effective in acute brain injury: brain trauma, brain infarction and hemorrhage. Should be given 2000 mg daily.
5. Effective in neurodevelopmental delay.
6. Effective in AD and bipolar disorder.
7. Effective in depression where it is given 100 mg 12 hourly with citalopram.

Indications of Use of Citicoline:

Citicoline is indicated in the following cases: patients with acute encephalopathy including acute and subacute cerebrovascular accident such as cerebral circulatory insufficiency, cerebral hemorrhage, cerebral palsy, and traumatic brain injury.

People use citicoline for age-related decline in memory and thinking, glaucoma, stroke, Alzheimer disease, bipolar disorder, depression, and many other conditions, but there is no good scientific research to support most of these uses. Don't confuse citicoline with choline or phosphatidylcholine (WebMed). As a dietary supplement, citicoline is used to boost brain performance and improve memory. It has also been investigated as a drug to treat a wide range of conditions, including stroke, dementia, bipolar disorder, and depression.

Citicoline has been proven to be a useful compound in preventing dementia progression. It also enhances cognitive functions among healthy individuals and improves prognosis after stroke. In an animal model of nerve damage and neuropathy, citicoline stimulated regeneration and lessened pain (NIH). This means citicoline is good for neuropathy and neuropathic pain.

Citicoline has been investigated for the treatment of depression, schizophrenia, stroke, Parkinson disease, brain injury, and cognitive deficits (i.e., mild to moderate dementia and Alzheimer disease, cerebrovascular disorders), as well as for its ophthalmologic effects. However, clinical trial results have been inconsistent; therefore, citicoline cannot be recommended for any indication. Oral dosages of 250 to 2,000 mg daily have been evaluated in adolescents and adults in clinical trials. Lower doses (100 mg twice daily) have been used in short-term trials (6 weeks) with combination therapy in patients with major depressive disorder.